FAQS

• What is a Genome? 

  The genome embodies the complete genetic blueprint of an individual. Whole genome sequencing (WGS) unravels the entirety of an individual's DNA code, encompassing all chromosomes inherited from both parental sources. It encapsulates the instructions for the intricate molecular mechanisms responsible for shaping your distinctive identity – essentially, your life's manuscript.

• Why is blood testing necessary? Is it possible to use a cheek swab instead?

  Blood testing is considered necessary due to its superior reliability and accuracy compared to cheek swab or oral samples. Cheek swabs may yield DNA of lower quality, resulting in a higher likelihood of false negatives. The DNA obtained from oral samples often lacks the optimal quality required for sequencing.

  Blood samples, on the other hand, provide a more comprehensive assessment as they contain DNA from both live and dead cells. This enables a thorough analysis of somatic and other variations, offering a complete Whole Genome Sequencing (WGS) analysis that is notably more accurate.

   

• What does Whole Genome Sequencing involve?

  Whole genome sequencing (WGS) stands as the pinnacle of genetic testing methodologies, examining every single component of your DNA, encompassing all 30,000 genes and meticulously assessing each chromosome from beginning to end. This method captures information about your complete genome, comprising more than 3 billion genetic variants.

  Whole genome sequencing stands unparalleled as the sole DNA test capable of capturing 100% of your genome. The gleaned data furnishes valuable insights essential for safeguarding your health across your lifetime. 

• What advantages does Whole Genome Sequencing offer?

  Through WGS analysis, genetic variations can be identified that elevate the likelihood of preventable illnesses. This comprehensive approach furnishes personalized health recommendations, aiding individuals in navigating potential disease risks and offering ongoing guidance for their well-being across their lifespan. 

• What categories of diseases/conditions does Whole Genome Sequencing assess?

  Whole Genome Sequencing delves into your genetic makeup, unveiling insights about disease susceptibility and inherited genes passed down from your parents. Recognizing that some individuals may prefer not to uncover certain disease risks, we offer customization options to tailor your analysis according to your preferences. To view a thorough compilation of test conditions, please click here.

• What's the process for conducting the test?

  The procedure is simple: begin by ordering a collection kit online, gather the sample in the comfort of your home, and subsequently, either mail it back or conveniently drop it off at any of the BioAro collection centers for sequencing and analysis. (You can find a list of BioAro Collection Centers in Canada or the US for your convenience.)

   

• What sets apart Whole Genome Sequencing from a standard DNA test?

  The code comprising an individual's DNA can be analysed using computational techniques and various methods to pinpoint mutations. The fundamental contrast lies in their scope: a typical DNA test scrutinizes only 1 to 2 percent of an individual's genetic makeup, whereas Whole Genome Sequencing scrutinizes the entirety of the person's genetic blueprint, encompassing the entire genome. 

• When is the ideal time for genomic testing?

  Genetic and microbiome testing is deemed safe at any point in life, even at birth. Every age bracket stands to gain valuable insights. This testing can offer a deeper understanding of current health status and potential health issues, serving as a tool for addressing health concerns both in the present and for the future.

  If my test results show no significant variants associated with a disease, does that guarantee immunity from the disease?
  Obtaining a clean result from genome sequencing doesn't assure absolute immunity from the analyzed disease. It signifies a reduced risk compared to others in the population, yet it doesn't eliminate the possibility of developing the disease. The onset of an illness isn't solely dictated by genetics but is also influenced by environmental factors and lifestyle choices. A negative result doesn't entirely rule out the potential for developing a specific disease.